VITAMIN A


VITAMIN A
Vitamin A was the first fat-soluble vitamin to be discovered…big surprise, as it’s named after the first letter of the alphabet! We obtain vitamin A from our diet in two forms: retinoids & carotenoids. Retinoids are the preformed vitamin A, meaning it’s readily active in the body; they’re found in foods of animal origin. On the other hand, carotenoids are the provitamins of vitamin A, meaning that they must be changed by the body into the active form of vitamin A; they’re present in fruits & vegetables which contain green, yellow, orange & red pigments called carotenes. Good sources of vitamin A include liver, cod liver oil, butter, ghee, cheese, egg yolk, milk, ready-to-eat cereals, amaranthus (terere), jews mallow (mrenda), spider plant (saga), black nightshade (managu), spinach, sweet potato, pumpkin, mango, papaya & carrots.



Now let’s talk about the super powers of this vitamin. It’s well understood function is in the normal functioning of the retina in the eye for clear vision in dim light, lack of vitamin A leads to impaired adaption to darkness. It boosts our immunity by regulating antibodies & maintaining mucous membranes, tissues, bones & skin cells which are the first line of defense against infections. A strong immunity is very important in managing sickle cell disease, therefore I consider this as the most important function of vitamin A in managing the condition. When we do not have enough vitamin A in our body, the mucous membrane linings become dry & rough which are easily invaded by micro-organisms that we inhale, ingest or touch; thus increasing susceptibility to infection. Furthermore, it supports reproduction & growth which may be greatly hindered by sickle cell disease. It also supports iron transport & mobilization as well as hematopoiesis (formation & development of blood cells). Lastly, like most of the other vitamins, β-carotene acts as an antioxidant capable of defending the red blood cells from oxidative damage by free radicals.
Eating foods rich in vitamin A can be easily achieved, especially because we are blessed as a nation to have such foods to be indigenous. However, most people make the mistake of losing vitamins in the way they prepare their meals. Vitamin A is lost when exposed to sunlight & upon dehydration of foods. This is why it’s always advisable to store most fruits & vegetables in cool dark areas. Remember that food can also get dehydrated even when there is no heat; avoid storing uncovered food in the refrigerator/ freezer for too long. In addition to this, we need to remember that vitamin A is fat- soluble. It therefore needs fats & oils to move around, so make sure you add healthy oils into your vegetables when cooking. You can always skip using oil when cooking your meats, trust me, they have enough oils of their own.

Supplementation of vitamin A is widely done in hospitals, mainly to those with immune-related illnesses. It is important to note that toxicity of vitamin A can easily occur with a single dose of 500,000IU or long-term intake of 50,000 IU per day. It can have adverse effects in pregnancy such as nausea, irritability, blurred vision, weakness, headaches, hair loss, dry skin & birth defects. To put it in a more realistic term, the common cod liver oil that we get from the pharmacy contains 7,000 IU of vitamin A per dose (10ml daily). Toxicity would mean taking 714ml (2 ½ cups) of cod liver oil daily. I don’t know about you, but I don’t fancy fish breath! It sounds impossible even insane to do this, but one can easily make this mistake when supplementing with capsules. They might be small, but they can be potent! So make sure you are on vitamin A supplementation only after prescription by a health expert. Let’s get our vitals kicking, with healthy eating.


Love life!
Sharlene M. M.



VITAMIN E

Vitamin E is a vitamin that dissolves in fat, just like vitamins A, D and K. It is found in a variety of foods, so including it in your diet should be a breeze! It’s in foods like, cereals, corn, wheat germ, meat, poultry, eggs, soy beans, olives, nuts (almonds, cashew, peanuts, hazelnuts, pine nuts & brazil nuts), sunflower seeds, spinach, fruits (avocado, mango, papaya & kiwi) and vegetable oils. It is also available as a supplement.


Vitamin E is an important vitamin required for the proper function of many organs in the body like the nerves, blood & muscle tissues. It is also an antioxidant; this means it helps to slow down processes that damage cells, just like vitamin C. Sickle erythrocytes (red blood cells) are more susceptible to oxidation damage than normal erythrocytes. This increased susceptibility to oxidation damage is, in part, due to decreased blood vitamin levels and abnormal membrane phospholipid organization induced by sickling. 
Check out the previous nutrition post on “Vitamin C” to know more on oxidative damage.
Remember, oxidation damage is NOT a good thing because it can produce abnormal cellular properties, such as increased red cell rigidity which can initiate episodes of capillary obstruction, leading to vaso-occlusive painful crises and to tissue infarction. The oxidation damage also causes increased hemolysis (breakdown of red blood cells), which leads to the release of a yellow substance called bilirubin into the blood. Bilirubin is normally excreted in bile and urine (in fact, it gives pee its colour) and elevated levels may indicate certain diseases –like jaundice where your eyes & skin become yellow. Presence of bilirubin in the blood may also cause a liver dysfunction due to bile sludging and decreased secretion of bile salts into the intestinal lumen, eventually leading to partial fat and vitamin E malabsorption.
Vitamin E is used for treating vitamin E deficiency, which is rare, but can occur in people with certain genetic disorders, such as sickle cell disease and in very low-weight premature infants. I recommend obtaining antioxidants, including vitamin E, by eating a well-balanced diet high in fruits, vegetables, and whole grains rather than from supplements until more is known about the risks and benefits of taking supplements. As said earlier, there is a wide variety of foods rich in vitamin E and other antioxidants; all you need to do is eat smart. So why don’t you join me in nibbling on some sunflower seeds in between meals? If that’s too odd & you feel like a pigeon in the park, try mixing the seeds with nuts or in baked foods. Much closer to home is the art of adding some avocado to your plate of githeri. So let’s hear it people, comment below & share your healthy mix-and-match-vitamin-combo meal…no matter how bizarre! No judgement, I promise
Happy healthy nibbles!
Love life!

Sharlene M.M.